Silexan (Lavender Oil Extract)

Class

Herbal anxiolytic

Mechanism

Thought to modulate voltage-dependent calcium channels and the serotonin system, leading to anxiolytic effects without sedation

FDA-Approved Use

None (herbal supplement with evidence in generalized anxiety disorder [GAD])

Off-Label Use

Situational anxiety, stress-related somatic symptoms

Formulation

Oral capsules (standardized lavender oil extract)

Titration

80 mg once daily

Dose Range

80 mg/day

Kinetics

Well absorbed orally; metabolism and half-life not well characterized

Common AEs

Gastrointestinal discomfort, belching, allergic skin reactions

Serious/Rare AEs

Rare hypersensitivity reactions

Monitoring

None routinely required; monitor for allergic reactions

Black Box Warning

None

Considerations

May be suitable for elderly patients or those with polypharmacy concerns due to low sedation and minimal drug interaction risk.